In a medical first, a mother who received a uterus transplant from a dead donor gave birth to a healthy baby, researchers reported on Wednesday. The breakthrough operation, performed in September 2016 in Sao Paulo, Brazil, shows that such transplants are feasible and could help thousands of women unable to have children due to uterine problems, according to a study published in The Lancet . The baby girl was born in December 2017. Until recently, the only options available to women with so-called uterine infertility were adoption or the services of a surrogate mother. The first successful childbirth following uterine transplant from a living donor took place in 2014 in Sweden, and there have been 10 others since then. Proof of concept But there are far more women in need of transplants than there are potential live donors, so doctors wanted to find out if the procedure could work using the uterus of a woman who had died. Ten attempts were made — in the U.S., the Czech Republic, and Turkey — before the success reported on Wednesday. Infertility affects 10 to 15% of couples. Of this group, one in 500 women have problems with their uterus — due, for example, to a malformation, hysterectomy, or infection — that prevent them from becoming pregnant and carrying a child to term. “Our results provide a proof-of-concept for a new option for women with uterine infertility,” said Dani Ejzenberg, a doctor at the University of Sao Paulo. He described the procedure as a “medical milestone”. “The number of people willing and committed to donate organs upon their own death are far larger than those of live donors, offering a much wider potential donor population,” he said.
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