MARBURG VIRUS DISEASE

  • Five people have died and three others are infected with the Marburg virus  in Tanzania.
  • Marburg virus disease (MVD), earlier known as Marburg hemorrhagic fever, is a severe, often fatal hemorrhagic fever.
  • Marburg, like Ebola, is a filovirus and both diseases are clinically similar.
  • Rousettus fruit bats are considered the natural hosts for the Marburg virus.
  • However, African green monkeys imported from Uganda were the source of the first human infection.

First detection:

It was first detected in 1967 after simultaneous outbreaks in Marburg and Frankfurt in Germany and in Belgrade, Serbia.

Fatality rate:

  • The disease has an average fatality rate of around 50%.
  • However, it can be as low as 24% or as high as 88% depending on virus strain and case management.

Symptoms:

  1. high fever,
  2. muscle aches
  3. severe headache
  4. abdominal pain,
  5. vomiting,
  6. severe watery diarrhoea and cramping.
  7. bleeding from the nose and gums and
  8. blood appearing in vomit and faeces.

Treatment:

  • It is difficult to clinically distinguish MVD from diseases such as malaria, typhoid fever and other viral haemorrhagic fevers.
  • It is confirmed by lab testing of samples, which like Coronavirus and Ebola are extreme biohazard risks.
  • There is no approved antiviral treatment or vaccine for MVD as of now.
  • It can be managed with supportive care.

SOURCE: THE HINDU, THE ECONOMIC TIMES, PIB

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