Mounjaro – Advanced Weight Loss & Diabetes Drug

GS II-Health

Context

US pharma company Eli Lilly is set to introduce Mounjaro in India. It is one of the most advanced weight loss drugs, primarily used for managing type 2 diabetes and now also approved for weight loss.

Key Ingredient & Mechanism

• Active Ingredient: Tirzepatide (a prescription-only injectable drug).
• How It Works:
  • Mimics two gut hormones—GLP-1 (Glucagon-Like Peptide-1) and GIP (Glucose-Dependent Insulinotropic Polypeptide).
  • Stimulates insulin release when blood sugar is high.
  • Reduces sugar production in the liver.
  • Slows digestion, creating a prolonged feeling of fullness, aiding in weight loss.

Advantage Over Semaglutide: Unlike semaglutide (which targets only GLP-1), Mounjaro affects both GLP-1 and GIP, making it more effective for both diabetes management and weight loss.

Benefits

Blood Sugar Control – Helps regulate glucose levels in diabetes patients.
Weight Loss – Clinical trials show 15-23% weight reduction.
Cardiovascular Protection – Lowers the risk of heart diseases.

Concerns

High Cost – Expensive, limiting accessibility.
Side Effects – May cause nausea, vomiting, and digestive issues.